In still another embodiment, the present invention provides an isolated population of solid tumor stem cells obtained from a solid tumor of epithelial origin, wherein the population comprises at least about 75 solid tumor stem cells and less than 25 solid tumor cells alternatively at least about 90 solid tumor stem cells and less than 10 solid tumor cells, wherein the solid tumor stem cells are tumorigenic; express low levels or undetectable levels of e cadherin; and, express elevated levels of SHC1 or FLJ20152 e <a href=
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